{"id":386,"date":"2016-09-05T00:57:52","date_gmt":"2016-09-04T16:57:52","guid":{"rendered":"http:\/\/lihua.me\/zh\/?p=386"},"modified":"2020-04-11T12:23:42","modified_gmt":"2020-04-11T04:23:42","slug":"febuxostat","status":"publish","type":"post","link":"https:\/\/lihua.me\/zh\/febuxostat\/","title":{"rendered":"\u6cbb\u75db\u98ce\u3001\u964d\u5c3f\u9178\u826f\u836f\uff1a\u975e\u5e03\u53f8\u4ed6"},"content":{"rendered":"\n<h4 class=\"wp-block-heading\">\u4e2a\u4eba\u60c5\u51b5<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">\u5927\u698210\u5e74\u524d\u53d1\u73b0\u6709\u9ad8\u5c3f\u9178\uff0c07\u5e74\u201411\u5e74\u524d\u540e\u6bcf\u5e74\u4f1a\u53d1\u4f5c\u4e00\u4e24\u6b21\u3002\u8fd9\u8ba9\u6211\u5f88\u62c5\u5fc3\uff0c\u4e00\u65b9\u9762\u662f\u611f\u53d7\u5f97\u5230\u7684\u75db\u75bc\uff0c\u53e6\u4e00\u65b9\u9762\u5c3f\u9178\u7ed3\u6676\u4f1a\u6c89\u79ef\u5728\u4f53\u5185\u7684\u5173\u8282\u3001\u5185\u810f\uff0c\u6015\u5bf9\u8eab\u4f53\u9020\u6210\u66f4\u52a0\u8d1f\u9762\u7684\u5f71\u54cd\u3002\u4e4b\u540e\u5c31\u6ce8\u610f\u996e\u98df\u4e86\uff0c\u6781\u5c11\u5403\u6d77\u9c9c\uff0c\u6781\u5c11\u559d\u9152\uff0c\u53d1\u4f5c\u5c31\u5c11\u4e86\uff0c\u4f46\u6bcf\u6b21\u4f53\u68c0\u7684\u65f6\u5019\u5c3f\u9178\u8fd8\u662f\u5f88\u9ad8\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6211\u7684\u5bb6\u65cf\u4e2d\uff0c\u7236\u4eb2\u3001\u4f2f\u7236\u3001\u5802\u5144\u3001\u8868\u5144\uff08\u59d1\u59d1\u7684\u513f\u5b50\uff09\uff0c\u751a\u81f3\u4f84\u513f\u90fd\u6709\u9ad8\u5c3f\u9178\uff0c\u6216\u8bb8\u9057\u4f20\u4e5f\u662f\u4e00\u4e2a\u91cd\u8981\u7684\u56e0\u7d20\uff0c\u57fa\u56e0\u4e0d\u597d\u6028\u4e0d\u5f97\u4eba\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u533b\u5b66\u4e0a\u770b\uff0c\u8981\u8ba4\u547d\uff0c\u5f88\u591a\u75be\u75c5\uff0c\u6bd4\u5982\u7cd6\u5c3f\u75c5\u3001\u8fd8\u6709\u9ad8\u5c3f\u9178\u75c7\u4ee5\u76ee\u524d\u7684\u533b\u5b66\u65e0\u6cd5\u6839\u6cbb\uff0c\u4e00\u4e9b\u6240\u8c13\u80fd\u591f\u6839\u6cbb\u7684\u504f\u65b9\u66f4\u591a\u662f\u5ffd\u60a0\u4eba\u3002\u65e2\u7136\u533b\u5b66\u4e0a\u65e0\u6cd5\u6839\u6cbb\uff0c\u5c31\u8981\u4e0e\u8fd9\u79cd\u75be\u75c5\u7ec8\u8eab\u76f8\u5904\u3002\u5c3d\u91cf\u964d\u4f4e\u8840\u5c3f\u9178\u662f\u7ec8\u6781\u7684\u89e3\u51b3\u65b9\u6848\uff0c\u4ece\u5b9e\u73b0\u65b9\u5f0f\u4e0a\u9762\u770b\uff0c\u6709\u4e24\u79cd\u7c7b\u578b\u7684\u836f\u7269\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>\u4e00\u79cd\u4fc3\u8fdb\u5c3f\u9178\u6392\u51fa<\/strong>\uff0c\u5e38\u7528\u836f\u6bd4\u5982<span class=\"st\">\u522b\u560c\u9187<\/span>\uff0c\u4f46\u522b\u560c\u9187\u5bf9\u4e8e\u90e8\u5206\u4eba\u7fa4\u53ef\u80fd\u5f15\u8d77\u8fc7\u654f\uff0c\u4e25\u91cd\u65f6\u751a\u81f3\u5bfc\u81f4\u6b7b\u4ea1\u3002<\/li><li><strong>\u4e00\u79cd\u836f\u7269\u51cf\u5c11\u5c3f\u9178\u5408\u6210<\/strong>\uff0c\u5982\u82ef\u6eb4\u9a6c\u9f99\uff0c\u5bf9\u80be\u810f\u4f24\u5bb3\u3002<\/li><\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u8fd1\u5e74\u65e5\u672c<strong>\u5e1d\u4eba\u836f\u4e1a<\/strong>\u7814\u53d1\u7684\u65b0\u836f<a href=\"https:\/\/en.wikipedia.org\/wiki\/Febuxostat\">\u975e\u5e03\u53f8\u4ed6<\/a>\uff0c\u901a\u8fc7\u51cf\u5c11\u5408\u6210\u7684\u65b9\u5f0f\u964d\u5c3f\u9178\uff0c<a href=\"http:\/\/www.haodf.com\/zhuanjiaguandian\/drxieyu_2602392115.htm\">\u526f\u4f5c\u7528\u6781\u5c0f<\/a>\uff0c\u53ea\u662f\u5f88\u8d35\u3002\u957f\u671f\u63a7\u5236\u8840\u5c3f\u9178\u7684\u6d53\u5ea6\uff0c\u4e5f\u53ef\u4ee5\u6eb6\u89e3\u5df2\u7ecf\u6c89\u79ef\u7684\u5c3f\u9178\u7ed3\u6676\uff0c\u51cf\u5c11\u5bf9\u5173\u8282\u3001\u5185\u810f\u7684\u4f24\u5bb3\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u66fe\u60f3\u8fc7\u4ece\u9999\u6e2f\u6216\u8005\u53f0\u6e7e\u8d2d\u4e70\uff0c\u65e0\u8bba\u81ea\u884c\u91c7\u8d2d\u8fd8\u662f\u4ee3\u8d2d\u90fd\u6bd4\u8f83\u9ebb\u70e6\u3002\u524d\u6bb5\u65f6\u95f4\u53bf\u57ce\u4eba\u6c11\u533b\u9662\u7684\u533b\u751f\u63a8\u8350\u4e86\u56fd\u4ea7\u5382\u5bb6\u751f\u4ea7\u7684<a href=\"http:\/\/yao.dxy.com\/drug\/144531.htm\">\u98ce\u5b9a\u5b81<\/a>\uff08\u4e0d\u77e5\u9053\u662f\u6388\u6743\u751f\u4ea7\uff0c\u8fd8\u662f\u4eff\u5236\uff09\uff0c\u53ef\u80fd\u56e0\u4e3a\u672c\u7701\u4f01\u4e1a\u751f\u4ea7\u6709\u653f\u5e9c\u6276\u6301\uff0c\u5c5e\u4e8e\u4e59\u7c7b\u533b\u4fdd\uff0c\u4ef7\u683c\u76f8\u5bf9\u4fbf\u5b9c\uff0c\u6bcf\u76d2 40mg*12 \u9897\uff0c\u533b\u4fdd\u4e4b\u540e\u7684\u4ef7\u683c\u5728 40 \u5143\u5de6\u53f3\uff0c\u5373\u4fbf\u6bcf\u5929\u5403\u4e24\u9897\u6bcf\u5e74\u4e5f\u53ea\u8981 2000 \u5143\uff0c\u8fd8\u5403\u5f97\u8d77\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6bcf\u5929 40mg\uff08\u4e00\u9897\uff09\u5403\u4e86\u4e09\u76d2\uff0c\u8840\u5c3f\u9178\u4e0d\u89c1\u4e0b\u6765\uff0c\u6539\u4e3a\u6bcf\u65e5 80mg\uff08\u4e24\u9897\uff09\uff0c\u5403\u4e86\u4e24\u5468\u8840\u5c3f\u9178\u964d\u5230 230 \u5de6\u53f3\uff0c\u518d\u6539\u4e3a\u6bcf\u65e5 40mg\u3002\u4ee5\u540e\u770b\u770b\u6548\u679c\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u51e0\u79cd\u7248\u672c\u7684\u975e\u5e03\u53f8\u4ed6<\/h2>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u56fd\u4ea7\uff08\u98ce\u5b9a\u5b81\uff09<\/strong><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">\u676d\u5dde\u6731\u517b\u5fc3\u836f\u4e1a\u6709\u9650\u516c\u53f8\u51fa\u54c1\uff0c\u836f\u623f\u7684\u4ef7\u683c\u6bd4\u8f83\u9ad8\uff0c\u8981300\u591a\u5143\uff0c40mg*12\uff0c\u533b\u9662\u4fbf\u5b9c\u5f88\u591a\u53ea\u8981137\u5143\u3002\u4e0d\u77e5\u9053\u662f\u4eff\u5236\u7684\u8fd8\u662f\u6b63\u5f0f\u6388\u6743\u7684\uff0c\u5982\u679c\u662f\u4eff\u5236\u90a3\u4e70\u73b0\u5728\u7684\u4ef7\u683c\u5c31\u592a\u9ed1\u4e86\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u9999\u6e2f\u7248\uff08\u83f2\u5e03\u529b\uff09<\/strong><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">\u5e1d\u4eba\u836f\u4e1a\u6388\u6743\u751f\u4ea7\uff0c80mg*28\u9897\uff0c\u4e00\u822c\u4ef7\u683c680\uff0c\u4f46\u662f\u5904\u65b9\u836f\uff0c\u9999\u6e2f\u6b63\u89c4\u7684\u836f\u5e97\u53ef\u80fd\u4e5f\u4e0d\u592a\u597d\u8d2d\u4e70\uff0c\u6bd4\u8f83\u7d27\u4fcf\uff0c\u4ef7\u683c\u6709\u65f6\u5019\u6da8\u4ef7\u5230900\u5143\u5de6\u53f3\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u53f0\u6e7e\u7248\uff08\u798f\u907f\u75db\uff09<\/strong><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">\u5e1d\u4eba\u836f\u4e1a\u6388\u6743\u751f\u4ea7\uff0c\u4ef7\u683c\u6bd4\u9999\u6e2f\u7248\u7684<strong>\u83f2\u5e03\u529b<\/strong>\u8981\u4fbf\u5b9c\u3002\u6709\u53ef\u9760\u6e20\u9053\u633a\u4e0d\u9519\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u4f7f\u7528\u975e\u5e03\u53f8\u4ed6\uff1a\u6613\u5165 5 \u5927\u8bef\u533a<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"http:\/\/www.clinphar.cn\/thread-365019-1-1.html\">\u6765\u6e90\uff1a\u4e01\u9999\u56ed<\/a> \u4f5c\u8005\uff1a\u5f90\u4e43\u4f73<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>\u5bf9\u8fdb\u884c\u964d\u5c3f\u9178\u6cbb\u7597\u7684\u75db\u98ce\u60a3\u8005\uff0c2016 \u7248\u300a\u4e2d\u56fd\u75db\u98ce\u8bca\u7597\u6307\u5357\u300b\uff08\u4ee5\u4e0b\u7b80\u79f0\u300a\u6307\u5357\u300b\uff09\u5c06\u975e\u5e03\u53f8\u4ed6\u8fdb\u884c\u4e86\u4e2d\u7b49\u7a0b\u5ea6\u7684\u63a8\u8350\u3002\u56e0\u5176\u4e34\u5e8a\u7597\u6548\u786e\u5b9e\u4e0d\u9519\uff0c\u975e\u5e03\u53f8\u4ed6\u5df2\u6210\u4e3a\u5185\u5206\u6ccc\u79d1\u3001\u98ce\u6e7f\u514d\u75ab\u79d1\u7684\u5e38\u7528\u836f\u3002\u7136\u800c\u7b14\u8005\u89c2\u5bdf\u5230\uff0c\u5728\u4f7f\u7528\u975e\u5e03\u53f8\u4ed6\u65f6\uff0c\u5f88\u5bb9\u6613\u5728\u9002\u5e94\u8bc1\u3001\u7528\u6cd5\u3001\u4e0d\u826f\u53cd\u5e94\u7b49\u65b9\u9762\u6b65\u5165\u8bef\u533a\u3002<\/p><p><strong>\u8bef\u533a\u4e00\uff1a\u9ad8\u5c3f\u9178\u8840\u75c7\u9700\u8981\u964d\u5c3f\u9178\u6cbb\u7597\u65f6\uff0c\u5747\u53ef\u4f7f\u7528\u975e\u5e03\u53f8\u4ed6<\/strong><\/p><p><span style=\"color: darkred;\">1. \u975e\u5e03\u53f8\u4ed6\u6700\u9002\u5408\u5c3f\u9178\u751f\u6210\u8fc7\u591a\u578b<\/span><\/p><p>2013 \u7248\u300a\u9ad8\u5c3f\u9178\u8840\u75c7\u548c\u75db\u98ce\u6cbb\u7597\u7684\u4e2d\u56fd\u4e13\u5bb6\u5171\u8bc6\u300b\uff08\u4ee5\u4e0b\u7b80\u79f0\u300a\u5171\u8bc6\u300b\uff09\u8ba4\u4e3a\uff0c\u6839\u636e\u8840\u5c3f\u9178\u6c34\u5e73\u548c\u5c3f\u5c3f\u9178\u6392\u6cc4\u60c5\u51b5\uff0c\u9ad8\u5c3f\u9178\u8840\u75c7\u53ef\u5206\u4e3a\u4e09\u578b\uff1a\u5c3f\u9178\u6392\u6cc4\u4e0d\u826f\u578b\u3001\u5c3f\u9178\u751f\u6210\u8fc7\u591a\u578b\u548c\u6df7\u5408\u578b\u3002\u975e\u5e03\u53f8\u4ed6\u901a\u8fc7\u9009\u62e9\u6027\u6291\u5236\u9ec4\u560c\u5464\u6c27\u5316\u9176\uff0c\u51cf\u5c11\u5c3f\u9178\u751f\u6210\u800c\u964d\u4f4e\u8840\u5c3f\u9178\u6c34\u5e73\uff0c\u6700\u9002\u5408\u5c3f\u9178\u751f\u6210\u8fc7\u591a\u578b\u3002\u56e0\u6b64\uff0c\u5728\u9009\u7528\u975e\u5e03\u53f8\u4ed6\u524d\uff0c\u6709\u6761\u4ef6\u7684\u8bdd\uff0c\u6700\u597d\u7559\u53d6 24 h \u5c3f\u68c0\u67e5\u5c3f\u5c3f\u9178\uff0c\u4ee5\u786e\u5b9a\u9ad8\u5c3f\u9178\u8840\u75c7\u7684\u7c7b\u578b\u3002<\/p><p><span style=\"color: darkred;\">2. \u4e0d\u63a8\u8350\u975e\u5e03\u53f8\u4ed6\u7528\u4e8e\u65e0\u75c7\u72b6\u7684\u9ad8\u5c3f\u9178\u8840\u75c7<\/span><\/p><p>\u53e6\u5916\uff0c\u975e\u5e03\u53f8\u4ed6\u836f\u7269\u8bf4\u660e\u4e66\u53ca\u300a\u5171\u8bc6\u300b\u6307\u660e\u975e\u5e03\u53f8\u4ed6\u9002\u7528\u4e8e\u75db\u98ce\u60a3\u8005\u7684\u9ad8\u5c3f\u9178\u8840\u75c7\uff0c\u800c\u4e0d\u63a8\u8350\u5176\u7528\u4e8e\u65e0\u75c7\u72b6\u7684\u9ad8\u5c3f\u9178\u8840\u75c7\u3002\u6b64\u836f\u672a\u505a\u5e94\u7528\u4e8e\u7ee7\u53d1\u6027\u9ad8\u5c3f\u9178\u8840\u75c7\u60a3\u8005\u7684\u7814\u7a76\uff0c\u56e0\u6b64\u7ee7\u53d1\u6027\u9ad8\u5c3f\u9178\u8840\u75c7\u60a3\u8005\u4e0d\u5efa\u8bae\u4f7f\u7528\u3002<\/p><p><strong>\u8bef\u533a\u4e8c\uff1a\u6bcf\u65e5 40 mg \u975e\u5e03\u53f8\u4ed6\uff0c\u670d\u7528 1 \u6708\u540e\u518d\u590d\u67e5\u8840\u5c3f\u9178<\/strong><\/p><p>\u300a\u5171\u8bc6\u300b\u53ca\u836f\u7269\u8bf4\u660e\u4e66\u63a8\u8350\uff1a\u53e3\u670d\u8d77\u59cb\u5242\u91cf\u4e3a 40 mg\uff0c\u6bcf\u65e5 1 \u6b21\u3002\u7531\u4e8e\u975e\u5e03\u53f8\u4ed6\u4e0e\u9ec4\u560c\u5464\u6c27\u5316\u9176\u5f62\u6210\u7684\u836f\u7269 &#8211; \u9176\u590d\u5408\u7269\u6781\u5176\u7a33\u5b9a\uff0c\u5176\u964d\u5c3f\u9178\u4f5c\u7528\u8f83\u522b\u560c\u5464\u9187\u66f4\u5f3a\uff0c\u6545\u670d\u7528 2 \u5468\u5373\u53ef\u590d\u67e5\u8840\u5c3f\u9178\u3002<br>\u82e5 2 \u5468\u540e\uff0c\u8840\u5c3f\u9178\u6c34\u5e73\u4ecd\u4e0d\u4f4e\u4e8e 360\u03bcmol\/L\uff0c\u5efa\u8bae\u5c06\u5242\u91cf\u589e\u81f3 80 mg\uff0c\u6bcf\u65e5 1 \u6b21\u3002<\/p><p><strong>\u8bef\u533a\u4e09\uff1a\u4f7f\u7528\u975e\u5e03\u53f8\u4ed6\u540e\uff0c\u8840\u5c3f\u9178\u672a\u8fbe\u6807\uff0c\u4e0d\u80fd\u518d\u4f7f\u7528\u5176\u5b83\u964d\u5c3f\u9178\u836f\u7269<\/strong><\/p><p>\u300a\u5171\u8bc6\u300b\u63a8\u8350\uff0c\u5982\u679c\u5355\u836f\u6cbb\u7597\u4e0d\u80fd\u4f7f\u8840\u5c3f\u9178\u8fbe\u6807\uff0c\u53ef\u4ee5\u5ba1\u614e\u8003\u8651\u8054\u5408\u6cbb\u7597\u3002<\/p><p>\u5982\u975e\u5e03\u53f8\u4ed6\u5728\u589e\u52a0\u5230\u9002\u5f53\u5242\u91cf\u540e\uff08\u4e00\u822c\u81f3 80mg\/ \u5929\u65f6\uff09\u4ecd\u4e0d\u80fd\u8fbe\u5230\u6cbb\u7597\u76ee\u6807\uff0c\u53ef\u4ee5\u8054\u5408\u4f7f\u7528\u4e00\u79cd\u4fc3\u8fdb\u5c3f\u9178\u6392\u6cc4\u836f\u7269\u3002\u5176\u5b83\u836f\u7269\u5305\u62ec\u975e\u8bfa\u8d1d\u7279\u3001\u6c2f\u6c99\u5766\u4e5f\u80fd\u4fc3\u8fdb\u5c3f\u9178\u6392\u6cc4\uff0c\u5728\u5408\u5e76\u9ad8\u8840\u538b\u6216\u9ad8\u7518\u6cb9\u4e09\u916f\u8840\u75c7\u65f6\uff0c\u53ef\u6839\u636e\u75c5\u60c5\u9009\u7528\u3002<\/p><p>\u9700\u8981\u6ce8\u610f\u7684\u662f\uff0c\u975e\u5e03\u53f8\u4ed6\u53ef\u80fd\u5f15\u8d77\u786b\u5511\u560c\u5464\u3001\u5def\u560c\u5464\u548c\u8336\u78b1\u7684\u8840\u836f\u6d53\u5ea6\u5347\u9ad8\uff0c\u6bd2\u6027\u589e\u52a0\u3002\u56e0\u6b64\uff0c\u7981\u6b62\u4e0e\u786b\u5511\u560c\u5464\u3001\u5def\u560c\u5464\u548c\u8336\u78b1\u5408\u7528\u3002<\/p><p><strong>\u8bef\u533a\u56db\uff1a\u975e\u5e03\u53f8\u4ed6\u5728\u809d\u4e2d\u4ee3\u8c22\u7ecf\u80be\u810f\u6392\u6cc4\uff0c\u809d\u80be\u529f\u80fd\u4e0d\u5168\u65f6\u4e0d\u5b9c\u4f7f\u7528<\/strong><\/p><p>\u975e\u5e03\u53f8\u4ed6\u4e3b\u8981\u5728\u809d\u810f\u4e2d\u4ee3\u8c22\uff0c\u4ee3\u8c22\u540e\u7684\u975e\u6d3b\u6027\u7269\u8d28 49% \u901a\u8fc7\u80be\u810f\u6392\u6cc4\u3001 45% \u7ecf\u8fc7\u7caa\u4fbf\u6392\u6cc4\uff0c\u8fd8\u6709\u7684\u7ecf\u8fc7\u80c6\u6c41\u6392\u6cc4\uff0c\u5c5e\u4e8e\u591a\u9014\u5f84\u6392\u6cc4\uff0c\u6240\u4ee5\u8f7b\u5ea6\u6216\u4e2d\u5ea6\u80be\u8870\u7aed\u60a3\u8005\uff08\u5185\u751f\u808c\u9150\u6e05\u9664\u7387 30\uff5e89 mL\/min\uff09\u53ca\u8f7b\u5ea6\u4e2d\u5ea6\uff08Child-Pugh A \u548c B \u7ea7\uff09\u809d\u529f\u80fd\u4e0d\u5168\u7684\u670d\u836f\u5242\u91cf\u65e0\u987b\u8c03\u6574\u3002<\/p><p>\u76ee\u524d\u8fd8\u6ca1\u6709\u5bf9\u91cd\u5ea6\u809d\u529f\u80fd\u4e0d\u5168\uff08Child-PughC \u7ea7\uff09\u548c\u91cd\u5ea6\u80be\u529f\u80fd\u4e0d\u5168\u7684\u60a3\u8005\u8fdb\u884c\u7814\u7a76\uff0c\u6240\u4ee5\u6b64\u7c7b\u60a3\u8005\u5728\u7528\u975e\u5e03\u53f8\u4ed6\u65f6\u8fd8\u662f\u8981\u614e\u91cd\u3002<\/p><p><strong>\u8bef\u533a\u4e94\uff1a\u975e\u5e03\u53f8\u4ed6\u5b89\u5168\u6027\u8f83\u9ad8\uff0c\u5c31\u5ffd\u7565\u5176\u4e0d\u826f\u53cd\u5e94\u7684\u53d1\u751f<\/strong><\/p><p>\u975e\u5e03\u53f8\u4ed6\u5bf9\u5176\u4ed6\u560c\u5464\u3001\u5627\u5576\u4ee3\u8c22\u7684\u9176\u65e0\u660e\u663e\u6d3b\u6027\uff0c\u4e0d\u4f1a\u5bf9\u9ec4\u560c\u5464\u6c27\u5316\u9176\u4e4b\u5916\u7684\u9176\u4ea7\u751f\u5f71\u54cd\uff0c\u4e0d\u4f1a\u4ea7\u751f\u4e0e\u522b\u560c\u9187\u7c7b\u4f3c\u7684\u6bd2\u526f\u4f5c\u7528\uff0c\u5b89\u5168\u6027\u8f83\u9ad8\u3002<\/p><p>\u7136\u800c\u836f\u65e0\u5b8c\u836f\uff0c\u548c\u522b\u560c\u9187\u4e00\u6837\uff0c\u975e\u5e03\u53f8\u4ed6\u4e5f\u4f1a\u51fa\u73b0\u76ae\u80a4\u8fc7\u654f\u53cd\u5e94\uff0c\u5728 2012 \u5e74\u7531\u7f8e\u56fd\u5b66\u8005\u9996\u6b21\u62a5\u9053\uff0c\u4e3b\u8981\u8868\u73b0\u4e3a\u76ae\u80a4\u7619\u75d2\u3001\u76ae\u75b9\u7b49\uff0c\u56fd\u5185\u4e5f\u6709\u7c7b\u4f3c\u4e34\u5e8a\u62a5\u9053\uff0c\u5982\u53d1\u751f\u5e38\u9700\u6297\u7ec4\u80fa\u836f\u3001\u7cd6\u76ae\u8d28\u6fc0\u7d20\u6cbb\u7597\uff0c\u4f7f\u7528\u8fc7\u7a0b\u4e2d\u5e94\u5f15\u8d77\u91cd\u89c6\u3002<\/p><p>\u8fd8\u8981\u63d0\u9192\u7684\u662f\uff0c\u809d\u529f\u80fd\u5f02\u5e38\u4e5f\u662f\u975e\u5e03\u53f8\u4ed6\u5e38\u89c1\u7684\u4e0d\u826f\u53cd\u5e94\u4e4b\u4e00\uff0c\u8868\u73b0\u4e3a\u75b2\u52b3\u3001\u98df\u6b32\u51cf\u9000\u3001\u9ec4\u75b8\u3001\u8179\u6cfb\u7b49\u60c5\u51b5\uff0c\u5982\u7528\u836f\u65f6\u51fa\u73b0\u4ee5\u4e0a\u72b6\u51b5\uff0c\u5e94\u68c0\u67e5\u809d\u529f\u80fd\uff0c\u786e\u8bca\u540e\u5e94\u4e2d\u6b62\u7528\u836f\uff0c\u5fc5\u8981\u65f6\u8fdb\u884c\u62a4\u809d\u6cbb\u7597\u3002<\/p><p>\u540c\u65f6\uff0c\u8d8a\u6765\u8d8a\u591a\u7684\u7814\u7a76\u53d1\u73b0\u975e\u5e03\u53f8\u4ed6\u6cbb\u7597\u65f6\u7684\u5fc3\u8840\u7ba1\u4e0d\u826f\u53cd\u5e94\uff0c\u5982\u51a0\u72b6\u52a8\u8109\u7ca5\u6837\u786c\u5316\u6027\u5fc3\u810f\u75c5\u3001\u5fc3\u529b\u8870\u7aed\u3001\u5fc3\u52a8\u8fc7\u7f13\u7b49\u3002\u76ee\u524d\u8fd8\u9700\u8981\u66f4\u591a\u7684\u5faa\u8bc1\u7814\u7a76\u8bc1\u660e\u975e\u5e03\u53f8\u4ed6\u4e0e\u5fc3\u8840\u7ba1\u4e0d\u826f\u53cd\u5e94\u7684\u56e0\u679c\u5173\u7cfb\u3002\u60a3\u8005\uff08\u5c24\u5176\u662f\u517c\u6709\u5fc3\u8840\u7ba1\u75be\u75c5\u8005\uff09\u670d\u7528\u975e\u5e03\u53f8\u4ed6\u540e\uff0c\u5e94\u6ce8\u610f\u5fc3\u8840\u7ba1\u7cfb\u7edf\u7684\u89c2\u5bdf\u3002<\/p><p>\u672c\u6587\u4f5c\u8005 | \u5f90\u4e43\u4f73\uff0c\u6e56\u5317\u6b66\u6c49\u5e02\u4e2d\u533b\u533b\u9662\u5185\u5206\u6ccc\u79d1\u4e3b\u6cbb\u533b\u751f<\/p><\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>\u4e2a\u4eba\u60c5\u51b5 \u5927\u698210\u5e74\u524d\u53d1\u73b0\u6709\u9ad8\u5c3f\u9178\uff0c07\u5e74\u201411\u5e74\u524d\u540e\u6bcf\u5e74\u4f1a\u53d1\u4f5c\u4e00\u4e24\u6b21\u3002\u8fd9\u8ba9\u6211\u5f88\u62c5\u5fc3\uff0c\u4e00\u65b9\u9762\u662f\u611f\u53d7\u5f97\u5230\u7684\u75db\u75bc\uff0c &hellip; <a href=\"https:\/\/lihua.me\/zh\/febuxostat\/\" class=\"more-link\">\u7ee7\u7eed\u9605\u8bfb<span class=\"screen-reader-text\">\u6cbb\u75db\u98ce\u3001\u964d\u5c3f\u9178\u826f\u836f\uff1a\u975e\u5e03\u53f8\u4ed6<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_crdt_document":"","iawp_total_views":8,"footnotes":""},"categories":[114],"tags":[399,417,415,416,398,400],"class_list":["post-386","post","type-post","status-publish","format-standard","hentry","category-health","tag-febuxostat","tag-417","tag-415","tag-416","tag-398","tag-400"],"_links":{"self":[{"href":"https:\/\/lihua.me\/zh\/wp-json\/wp\/v2\/posts\/386","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lihua.me\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lihua.me\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lihua.me\/zh\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/lihua.me\/zh\/wp-json\/wp\/v2\/comments?post=386"}],"version-history":[{"count":0,"href":"https:\/\/lihua.me\/zh\/wp-json\/wp\/v2\/posts\/386\/revisions"}],"wp:attachment":[{"href":"https:\/\/lihua.me\/zh\/wp-json\/wp\/v2\/media?parent=386"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lihua.me\/zh\/wp-json\/wp\/v2\/categories?post=386"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lihua.me\/zh\/wp-json\/wp\/v2\/tags?post=386"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}